8-(2,6-Difluoro-3,5-dimethoxy-phenyl)quinoxaline-5-carboxylic acid → 8-(2,6-Difluoro-3,5-dimethoxy-phenyl)-quinoxaline-5-carboxylic acid [6-(4-ethyl-piperazin-1-ylmethyl)-pyridin-3-yl]-amide
Reaction equation
[CH2:26]([CH3:27])[N:28]1[CH2:29][CH2:30][N:31]([CH2:34][c:35]2[cH:36][cH:37][c:38]([NH2:41])[cH:39][n:40]2)[CH2:32][CH2:33]1.[F:1][c:2]1[c:3](-[c:13]2[cH:14][cH:15][c:16]([C:23](=[O:24])[OH:25])[c:17]3[n:18][cH:19][cH:20][n:21][c:22]23)[c:4]([F:12])[c:5]([O:10][CH3:11])[cH:6][c:7]1[O:8][CH3:9]>>[F:1][c:2]1[c:3](-[c:13]2[cH:14][cH:15][c:16]([C:23](=[O:25])[NH:41][c:38]3[cH:37][cH:36][c:35]([CH2:34][N:31]4[CH2:30][CH2:29][N:28]([CH2:26][CH3:27])[CH2:33][CH2:32]4)[n:40][cH:39]3)[c:17]3[n:18][cH:19][cH:20][n:21][c:22]23)[c:4]([F:12])[c:5]([O:10][CH3:11])[cH:6][c:7]1[O:8][CH3:9]Participants
3
Sources & evidence
- ORD record
- ord-dfb4816f18c641c789cd337893ea4db7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…