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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 673765Generated: October 30, 2026

Toluene → Methyl 4,4-difluoro-3-oxo-2-(morpholin-4-ylmethylidene)butyrate

https://huagongshe.com/reaction/673765

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantTriethylamineHCID 8471—
ReactantMethyl 3-morpholin-4-ylacrylateHCID 351261—
Reactant2,2-Difluoroacetyl fluorideHCID 2778914—
ProductMethyl 4,4-difluoro-3-oxo-2-(morpholin-4-ylmethylidene)butyrateHCID 86651360—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-24de6936de0f4d17b8165a43a098f505
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)