4-(1-Pyrrolidinyl)piperidine → HCID 57580526, compound

HRID 673820Notes

Reaction equation

HRID 673820 reaction equation
[Br:1][c:2]1[cH:3][c:4]([CH3:21])[c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][CH:13]([N:16]3[CH2:17][CH2:18][CH2:19][CH2:20]3)[CH2:14][CH2:15]2)[cH:6][cH:7]1.[Br:22][c:23]1[cH:24][cH:25][c:26]([C:27]([OH:28])=[O:29])[c:30]([CH3:31])[cH:32]1.[Br:44][c:45]1[c:46]([CH3:47])[c:48]([C:49]([N:50]2[CH2:51][CH2:52][CH:53]([N:54]3[CH2:55][CH2:56][CH2:57][CH2:58]3)[CH2:59][CH2:60]2)=[O:61])[cH:62][cH:63][cH:64]1.[F:65][C:66]([O:67][c:68]1[cH:69][c:70]([B:74]([OH:75])[OH:76])[cH:71][cH:72][cH:73]1)([F:77])[F:78].[N:33]1([CH:34]2[CH2:35][CH2:36][NH:37][CH2:38][CH2:39]2)[CH2:40][CH2:41][CH2:42][CH2:43]1>>[c:2]1(-[c:70]2[cH:69][c:68]([O:67][C:66]([F:65])([F:77])[F:78])[cH:73][cH:72][cH:71]2)[cH:3][c:4]([CH3:21])[c:5]([C:8](=[O:9])[N:10]2[CH2:11][CH2:12][CH:13]([N:16]3[CH2:17][CH2:18][CH2:19][CH2:20]3)[CH2:14][CH2:15]2)[cH:6][cH:7]1

Participants

6

Reactant 5

HCID 787034-(1-Pyrrolidinyl)piperidineHCID 995704-Bromo-2-methylbenzoic acidHCID 27343853-(Trifluoromethoxy)phenylboronic Acid (contains varying amounts of Anhydride)HCID 65573179HCID 65573179, compoundHCID 66901611HCID 66901611, compound

Product 1

HCID 57580526HCID 57580526, compound

Sources & evidence

ORD record
ord-167b87a34c514490947668d8776b0a08
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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