1-(1-Methyl-4-piperidinyl)piperazine → (4-{2-[4-(1-Methyl-piperidin-4-yl)-piperazin-1-yl]-2-oxo-ethyl}-thiazol-2-yl)-carbamic acid tert-butyl ester

HRID 674289Notes

Reaction equation

HRID 674289 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][c:9]1[s:10][cH:11][c:12]([CH2:14][C:15](=[O:16])[OH:17])[n:13]1.[CH3:18][N:19]1[CH2:20][CH2:21][CH:22]([N:25]2[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]2)[CH2:23][CH2:24]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][c:9]1[s:10][cH:11][c:12]([CH2:14][C:15](=[O:17])[N:28]2[CH2:27][CH2:26][N:25]([CH:22]3[CH2:21][CH2:20][N:19]([CH3:18])[CH2:24][CH2:23]3)[CH2:30][CH2:29]2)[n:13]1

Participants

3

Reactant 2

HCID 5663241-(1-Methyl-4-piperidinyl)piperazineHCID 154800062-(2-((tert-Butoxycarbonyl)amino)thiazol-4-yl)acetic acid

Product 1

HCID 59698869(4-{2-[4-(1-Methyl-piperidin-4-yl)-piperazin-1-yl]-2-oxo-ethyl}-thiazol-2-yl)-carbamic acid tert-butyl ester

Sources & evidence

ORD record
ord-bb0c68f6f66d40b6b30b6e1c3820335e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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