1-Methyl-1H-indole-2-carbonyl chloride → N-[4-(4-amino-7-{[3-(4-hydroxypiperidin-1-yl)propanoyl]amino}thieno[3,2-c]pyridin-3-yl)-2-methoxyphenyl]-1-methyl-1H-indole-2-carboxamide

HRID 674310Notes

Reaction equation

HRID 674310 reaction equation
[CH3:1][n:2]1[c:3]([C:11](=[O:12])[Cl:13])[cH:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]12.[NH2:14][c:15]1[n:16][cH:17][c:18]([NH:33][C:34]([CH2:35][CH2:36][N:37]2[CH2:38][CH2:39][CH:40]([OH:43])[CH2:41][CH2:42]2)=[O:44])[c:19]2[c:20]1[c:21](-[c:24]1[cH:25][c:26]([O:31][CH3:32])[c:27]([NH2:30])[cH:28][cH:29]1)[cH:22][s:23]2>>[CH3:1][n:2]1[c:3]([C:11](=[O:12])[NH:30][c:27]2[c:26]([O:31][CH3:32])[cH:25][c:24](-[c:21]3[c:20]4[c:15]([NH2:14])[n:16][cH:17][c:18]([NH:33][C:34]([CH2:35][CH2:36][N:37]5[CH2:38][CH2:39][CH:40]([OH:43])[CH2:41][CH2:42]5)=[O:44])[c:19]4[s:23][cH:22]3)[cH:29][cH:28]2)[cH:4][c:5]2[cH:6][cH:7][cH:8][cH:9][c:10]12

Participants

3

Reactant 2

HCID 123033141-Methyl-1H-indole-2-carbonyl chlorideHCID 18451406HCID 18451406, compound

Product 1

HCID 18451117N-[4-(4-amino-7-{[3-(4-hydroxypiperidin-1-yl)propanoyl]amino}thieno[3,2-c]pyridin-3-yl)-2-methoxyphenyl]-1-methyl-1H-indole-2-carboxamide

Sources & evidence

ORD record
ord-28eeb243dd304e5f874ecddc8612fe1a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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