Water → N-(4-[4-(Tetrahydro-2-oxo-1(2H)-pyrimidinyl)-1-piperidinyl]-2-(4-chlorophenyl)-butyl)-N-methyl-5,6,7,8-tetrahydro-1-naphthamide
Reaction equation
[C:40]([O-:41])(=[O:42])[CH2:43][C:44]([CH2:45][C:46]([O-:47])=[O:48])([C:49]([O-:50])=[O:51])[OH:52].[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH2:9][N:10]([C:11](=[O:12])[c:13]2[cH:14][cH:15][cH:16][c:17]3[c:22]2[CH2:21][CH2:20][CH2:19][CH2:18]3)[CH3:23])[CH2:24][CH:25]=[O:26])[cH:6][cH:7]1.[O:27]=[C:28]1[N:29]([CH:34]2[CH2:35][CH2:36][NH:37][CH2:38][CH2:39]2)[CH2:30][CH2:31][CH2:32][NH:33]1.[OH2:53]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([CH:8]([CH2:9][N:10]([C:11](=[O:12])[c:13]2[cH:14][cH:15][cH:16][c:17]3[c:22]2[CH2:21][CH2:20][CH2:19][CH2:18]3)[CH3:23])[CH2:24][CH2:25][N:37]2[CH2:36][CH2:35][CH:34]([N:29]3[C:28](=[O:27])[NH:33][CH2:32][CH2:31][CH2:30]3)[CH2:39][CH2:38]2)[cH:6][cH:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-437b4ef50fc5492f8d6465aa913267dc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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