4-Chloro-2-(trifluoromethyl)benzoic acid → 4-chloro-N-(2-pyrrolidin-1-ylcyclopentyl)-2-(trifluoromethyl)benzamide

HRID 674332Notes

Reaction equation

HRID 674332 reaction equation
[Cl:12][c:13]1[cH:14][c:15]([C:22]([F:23])([F:24])[F:25])[c:16]([C:17](=[O:18])[OH:19])[cH:20][cH:21]1.[N:1]1([CH:6]2[CH:7]([NH2:11])[CH2:8][CH2:9][CH2:10]2)[CH2:2][CH2:3][CH2:4][CH2:5]1>>[N:1]1([CH:6]2[CH:7]([NH:11][C:17]([c:16]3[c:15]([C:22]([F:23])([F:24])[F:25])[cH:14][c:13]([Cl:12])[cH:21][cH:20]3)=[O:18])[CH2:8][CH2:9][CH2:10]2)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

3

Reactant 2

HCID 27738564-Chloro-2-(trifluoromethyl)benzoic acidHCID 167924612-(Pyrrolidin-1-yl)cyclopentan-1-amine

Product 1

HCID 666811534-chloro-N-(2-pyrrolidin-1-ylcyclopentyl)-2-(trifluoromethyl)benzamide

Sources & evidence

ORD record
ord-a53e47ea1d254e9bba338cc0be1d0476
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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