1,3-Dibromo-5-fluorobenzene → 6-(3-Bromo-5-fluoro-phenyl)4,4-dicyclopropyl-1,4-dihydrobenzo-[d][1,3]oxazin-2-one

HRID 674396Notes

Reaction equation

HRID 674396 reaction equation
[Br:21][c:22]1[cH:23][c:24]([Br:29])[cH:25][c:26]([F:28])[cH:27]1.[CH:1]1([C:4]2([CH:18]3[CH2:19][CH2:20]3)[O:5][C:6](=[O:17])[NH:7][c:8]3[c:9]2[cH:10][c:11]([B:14]([OH:15])[OH:16])[cH:12][cH:13]3)[CH2:2][CH2:3]1>>[CH:1]1([C:4]2([CH:18]3[CH2:19][CH2:20]3)[O:5][C:6](=[O:17])[NH:7][c:8]3[c:9]2[cH:10][c:11](-[c:24]2[cH:23][c:22]([Br:21])[cH:27][c:26]([F:28])[cH:25]2)[cH:12][cH:13]3)[CH2:2][CH2:3]1

Participants

3

Reactant 2

HCID 1370031,3-Dibromo-5-fluorobenzeneHCID 23509592(4,4-dicyclopropyl-1,4-dihydro-2-oxo-2H-3,1-benzoxazin-6-yl)boronic acid

Product 1

HCID 101579196-(3-Bromo-5-fluoro-phenyl)4,4-dicyclopropyl-1,4-dihydrobenzo-[d][1,3]oxazin-2-one

Sources & evidence

ORD record
ord-cf16e66e9f6746c1948b1bb24fb7da9a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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