HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 9-methyl-6-triisopropylsilanyloxy-2,3,4,9-tetrahydro-1H-beta-carboline trifluoroacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 9-Methyl-6-triisopropylsilanyloxy-1,3,4,9-tetrahydro-beta-carboline-2-carboxylic acid tert-butyl ester | HCID 23544276 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 9-methyl-6-triisopropylsilanyloxy-2,3,4,9-tetrahydro-1H-beta-carboline trifluoroacetate | HCID 22018481 | — |
Reaction Steps
A solution of 9-methyl-6-triisopropylsilanyloxy-1,3,4,9-tetrahydro-β-carboline-2-carboxylic acid tert-butyl ester (175 mg) and 0.5 mL of trifluoroacetic acid in 3 mL dichloromethane was stirred for 4 h. The solvent was removed to afford 9-methyl-6-triisopropylsilanyloxy-2,3,4,9-tetrahydro-1H-β-carboline trifluoroacetate (125 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07084154B2 |
| Source dataset | uspto-grants-2006_08 |
| ORD ID | ord-635cce29b8b9494caf7fd86a177b023b |
| Source note | uspto-grants-2006_08 |