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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 674819Generated: October 30, 2026

Methanol → N-[5-(2,2-dimethyl-1,3-dioxolan-4-yl)pyrazin-2-yl]-4-methylsulfanyl-2-[3-oxo-7-(trifluoromethyl)-1H-isoindol-2-yl]butanamide

https://huagongshe.com/reaction/674819

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantDimethylformamideHCID 6228—
ReactantDichloromethaneHCID 6344—
Reactant2,6-LutidineHCID 7937—
ReactantOxalyl chlorideHCID 65578—
Reactant5-(2,2-Dimethyl-1,3-dioxolan-4-yl)pyrazin-2-amineHCID 21897304—
Reactant4-methylsulfanyl-2-[3-oxo-7-(trifluoromethyl)-1H-isoindol-2-yl]butanoic acidHCID 70944913—
ProductN-[5-(2,2-dimethyl-1,3-dioxolan-4-yl)pyrazin-2-yl]-4-methylsulfanyl-2-[3-oxo-7-(trifluoromethyl)-1H-isoindol-2-yl]butanamideHCID 70945446—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-06a905d930a44a6da1839f2779072de9
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)