Pyridine → 5-(5-chloro-1,2,4-thiadiazol-3-yl)-N-[5-(3,5-dimethylpiperazin-1-yl)-2-methoxyphenyl]thiophene-2-sulfonamide

HRID 675044Notes

Reaction equation

HRID 675044 reaction equation
[CH3:1][CH:2]1[CH2:3][N:4]([c:9]2[cH:10][cH:11][c:12]([O:16][CH3:17])[c:13]([NH2:14])[cH:15]2)[CH2:5][CH:6]([CH3:8])[NH:7]1.[Cl:18][c:19]1[n:20][c:21](-[c:24]2[cH:25][cH:26][c:27]([S:29](=[O:30])(=[O:31])[Cl:32])[s:28]2)[n:22][s:23]1.[Cl:33][CH2:34][Cl:35].[cH:36]1[cH:37][cH:38][n:39][cH:40][cH:41]1>>[CH3:1][CH:2]1[CH2:3][N:4]([c:9]2[cH:10][cH:11][c:12]([O:16][CH3:17])[c:13]([NH:14][S:29]([c:27]3[cH:26][cH:25][c:24](-[c:21]4[n:20][c:19]([Cl:18])[s:23][n:22]4)[s:28]3)(=[O:30])=[O:31])[cH:15]2)[CH2:5][CH:6]([CH3:8])[NH:7]1

Participants

5

Reactant 4

HCID 1049PyridineHCID 6344DichloromethaneHCID 27358205-(5-chloro-1,2,4-thiadiazol-3-yl)thiophene-2-sulfonyl ChlorideHCID 691944835-(3,5-Dimethylpiperazin-1-yl)-2-methoxyaniline

Product 1

HCID 691981545-(5-chloro-1,2,4-thiadiazol-3-yl)-N-[5-(3,5-dimethylpiperazin-1-yl)-2-methoxyphenyl]thiophene-2-sulfonamide

Sources & evidence

ORD record
ord-f9cf6380f27a4d09a5ec1b732803dea7
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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