Acetone → 2-(4-Chloro-2-fluorophenyl)-2,3,4,5,6,7-hexahydro-3-methylthio-1H-isoindol-1-one
Reaction equation
[C:22](=[O:23])([O-:24])[O-:25].[CH3:20][I:21].[CH3:28][C:29](=[O:30])[CH3:31].[Cl:1][c:2]1[cH:3][c:4]([F:19])[c:5]([N:8]2[C:9](=[O:18])[C:10]3=[C:15]([CH2:14][CH2:13][CH2:12][CH2:11]3)[CH:16]2[SH:17])[cH:6][cH:7]1.[K+:26].[K+:27]>>[Cl:1][c:2]1[cH:3][c:4]([F:19])[c:5]([N:8]2[C:9](=[O:18])[C:10]3=[C:15]([CH2:14][CH2:13][CH2:12][CH2:11]3)[CH:16]2[S:17][CH3:22])[cH:6][cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-6dfee109d3794762af02cfc30cc20604
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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