Dichloromethane → 4-(1-Bromopropan-2-yloxy)-7-methoxyquinoline

HRID 675199Notes

Reaction equation

HRID 675199 reaction equation
[CH3:18][O:19][c:20]1[cH:21][cH:22][c:23]2[c:24]([O:30][CH:31]([CH2:32][OH:33])[CH3:34])[cH:25][cH:26][n:27][c:28]2[cH:29]1.[CH3:1][O:2][c:3]1[cH:4][c:5]2[c:6]([c:7]([O:8][CH2:9][CH:10]([OH:11])[CH3:12])[cH:13][cH:14][n:15]2)[cH:16][cH:17]1.[Cl:39][CH2:40][Cl:41].[P:35]([Br:36])([Br:37])[Br:38]>>[CH3:18][O:19][c:20]1[cH:21][cH:22][c:23]2[c:24]([O:30][CH:31]([CH2:32][Br:36])[CH3:34])[cH:25][cH:26][n:27][c:28]2[cH:29]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 24614Phosphorus tribromideHCID 688094362-(7-Methoxyquinolin-4-yloxy)propan-1-olHCID 688118821-(7-Methoxyquinolin-4-yloxy)propan-2-ol

Product 1

HCID 598430804-(1-Bromopropan-2-yloxy)-7-methoxyquinoline

Sources & evidence

ORD record
ord-c511135dfb9c409ba6288043640fee84
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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