Acetone → 8-Chloro-5-fluoro-4-methoxy-2-(trifluoromethyl)quinoline
Reaction equation
[CH3:26][C:27](=[O:28])[CH3:29].[Cl:1][c:2]1[cH:3][cH:4][c:5]([F:17])[c:6]2[c:7]([OH:16])[cH:8][c:9]([C:12]([F:13])([F:14])[F:15])[n:10][c:11]12.[I:24][CH3:25].[K+:18].[K+:19].[O-:20][C:21]([O-:22])=[O:23]>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([F:17])[c:6]2[c:7]([O:16][CH3:21])[cH:8][c:9]([C:12]([F:13])([F:14])[F:15])[n:10][c:11]12Participants
6
Sources & evidence
- ORD record
- ord-ddfd3c6485d14a8e9a3170361054b6a8
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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