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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 675448Generated: October 30, 2026

Dichloromethane → N-[1-(1,3-dioxoisoindol-2-yl)-3-[2-(trifluoromethyl)phenyl]propan-2-yl]-5-ethyl-4-(2-methylpyrazol-3-yl)thiophene-2-carboxamide

https://huagongshe.com/reaction/675448

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantHexafluorophosphateHCID 9886—
ReactantDiisopropylethylamineHCID 81531—
ReactantBromotripyrrolidin-1-ylphosphoniumHCID 2733180—
Reactant5-ethyl-4-(1-methyl-1H-pyrazol-5-yl)-2-thiophenecarboxylic acidHCID 57826748—
Reactant2-[2-amino-3-[2-(trifluoromethyl)phenyl]propyl]isoindole-1,3-dioneHCID 178510762—
ProductN-[1-(1,3-dioxoisoindol-2-yl)-3-[2-(trifluoromethyl)phenyl]propan-2-yl]-5-ethyl-4-(2-methylpyrazol-3-yl)thiophene-2-carboxamideHCID 76576564—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-f6f541b781e341f883600d56e12a0e3f
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)