Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 675479Generated: October 25, 2026

Dichloromethane → 2-[2-(Isopropylamino-methyl)-pyrrolidin-1-yl]-3-methyl-5-naphthalen-2-yl-6-pyridin-4-yl-3H-pyrimidin-4-one

https://huagongshe.com/reaction/675479

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantDiisopropylethylamineHCID 81531—
Reactant5-(3-Bromo-phenyl)-2-chloro-3-methyl-6-pyridin-4-yl-3H-pyrimidin-4-oneHCID 22185186—
Reactant2-Chloro-3-methyl-5-naphthalen-2-yl-6-pyridin-4-yl-3H-pyrimidin-4-oneHCID 22185193—
ReactantN-(Pyrrolidin-2-ylmethyl)propan-2-amineHCID 22185196—
Product2-[2-(Isopropylamino-methyl)-pyrrolidin-1-yl]-3-methyl-5-naphthalen-2-yl-6-pyridin-4-yl-3H-pyrimidin-4-oneHCID 22185209—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-b87091ea467b402caa6c417837f3e3c2
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)