Methanol → (2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-methyl-(1-methyl-1H-imidazol-4-ylmethyl)-amine

HRID 675571Notes

Reaction equation

HRID 675571 reaction equation
[CH3:20][n:21]1[cH:22][n:23][c:24]([CH:26]=[O:27])[cH:25]1.[CH3:28][CH2:29][O:30][CH2:31][CH3:32].[CH3:33][OH:34].[Cl:1][c:2]1[n:3][c:4]([N:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][NH:12][CH3:13])[s:10]2>>[Cl:1][c:2]1[n:3][c:4]([N:14]2[CH2:15][CH2:16][O:17][CH2:18][CH2:19]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:12]([CH3:13])[CH2:26][c:24]1[n:23][cH:22][n:21]([CH3:20])[cH:25]1)[s:10]2

Participants

5

Reactant 4

HCID 887MethanolHCID 3283Diethyl EtherHCID 5734191-Methyl-1H-imidazole-4-carbaldehydeHCID 595929371-(2-Chloro-4-morpholinothieno[3,2-d]pyrimidin-6-yl)-N-methylmethanamine

Product 1

HCID 86623542(2-chloro-4-morpholin-4-yl-thieno[3,2-d]pyrimidin-6-ylmethyl)-methyl-(1-methyl-1H-imidazol-4-ylmethyl)-amine

Sources & evidence

ORD record
ord-62b2c7c212ec432fb9b46f4eaabb5215
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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