Sodium ion → 5-Chloro-1'-[3-(4-chlorophenyl)prop-2-enyl]spiro[1,2-dihydroindole-3,3'-pyrrolidine]

HRID 675662Notes

Reaction equation

HRID 675662 reaction equation
[CH3:1][S:2](=[O:3])(=[O:4])[N:5]1[CH2:6][C:7]2([c:8]3[cH:9][c:10]([Cl:14])[cH:11][cH:12][c:13]31)[CH2:15][N:16]([CH2:19][CH:20]=[CH:21][c:22]1[cH:23][cH:24][c:25]([Cl:28])[cH:26][cH:27]1)[CH2:17][CH2:18]2.[CH3:30][O:31][CH2:32][CH2:33][O:34][Al+:35][O:36][CH2:37][CH2:38][O:39][CH3:40].[CH3:43][c:44]1[cH:45][cH:46][cH:47][cH:48][cH:49]1.[H-:29].[H-:42].[Na+:41]>>[NH:5]1[CH2:6][C:7]2([c:8]3[cH:9][c:10]([Cl:14])[cH:11][cH:12][c:13]31)[CH2:15][N:16]([CH2:19][CH:20]=[CH:21][c:22]1[cH:23][cH:24][c:25]([Cl:28])[cH:26][cH:27]1)[CH2:17][CH2:18]2

Participants

6

Reactant 5

HCID 923Sodium ionHCID 1140TolueneHCID 166653Hydride2×HCID 18764105Bis(2-methoxyethoxy)alumanyliumHCID 689242435-chloro-1'-[3-(4-chlorophenyl)prop-2-enyl]-1-methylsulfonylspiro[2H-indole-3,3'-pyrrolidine]

Product 1

HCID 689306525-Chloro-1'-[3-(4-chlorophenyl)prop-2-enyl]spiro[1,2-dihydroindole-3,3'-pyrrolidine]

Sources & evidence

ORD record
ord-31ea5e9716374575a2bc444cd4ad4754
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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