1-(4-Fluorophenyl)cyclopentanecarboxylic acid → N-(3-{4-[3-(butyrylamino)-4-fluorophenyl]-1-piperidinyl}propyl)-1-(4-fluorophenyl)cyclopentanecarboxamide

HRID 675763Notes

Reaction equation

HRID 675763 reaction equation
[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([C:13](=[O:14])[OH:15])[CH2:9][CH2:10][CH2:11][CH2:12]2)[cH:6][cH:7]1.[NH2:16][CH2:17][CH2:18][CH2:19][N:20]1[CH2:21][CH2:22][CH:23]([c:26]2[cH:27][cH:28][c:29]([F:38])[c:30]([NH:32][C:33]([CH2:34][CH2:35][CH3:36])=[O:37])[cH:31]2)[CH2:24][CH2:25]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([C:8]2([C:13](=[O:15])[NH:16][CH2:17][CH2:18][CH2:19][N:20]3[CH2:21][CH2:22][CH:23]([c:26]4[cH:27][cH:28][c:29]([F:38])[c:30]([NH:32][C:33]([CH2:34][CH2:35][CH3:36])=[O:37])[cH:31]4)[CH2:24][CH2:25]3)[CH2:9][CH2:10][CH2:11][CH2:12]2)[cH:6][cH:7]1

Participants

3

Reactant 2

HCID 7361331-(4-Fluorophenyl)cyclopentanecarboxylic acidHCID 21957132N-{5-[1-(3-aminopropyl)4-piperidinyl]-2-fluorophenyl}butanamide

Product 1

HCID 21957119N-(3-{4-[3-(butyrylamino)-4-fluorophenyl]-1-piperidinyl}propyl)-1-(4-fluorophenyl)cyclopentanecarboxamide

Sources & evidence

ORD record
ord-00564289af93470fa6e18d96265cf2c9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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