Methanol → 5-Pyrimidin-2-yl-1-({4-[5-(2,2,2-trifluoroethoxy)pyrimidin-2-yl]piperazin-1-yl}sulfonyl)pentan-2-ol
Reaction equation
[BH4-:34].[CH3:39][OH:40].[Cl:36][CH2:37][Cl:38].[Na+:35].[n:1]1[c:2]([CH2:7][CH2:8][CH2:9][C:10]([CH2:11][S:12](=[O:13])(=[O:14])[N:15]2[CH2:16][CH2:17][N:18]([c:21]3[n:22][cH:23][c:24]([O:27][CH2:28][C:29]([F:30])([F:31])[F:32])[cH:25][n:26]3)[CH2:19][CH2:20]2)=[O:33])[n:3][cH:4][cH:5][cH:6]1>>[n:1]1[c:2]([CH2:7][CH2:8][CH2:9][CH:10]([CH2:11][S:12](=[O:13])(=[O:14])[N:15]2[CH2:16][CH2:17][N:18]([c:21]3[n:22][cH:23][c:24]([O:27][CH2:28][C:29]([F:30])([F:31])[F:32])[cH:25][n:26]3)[CH2:19][CH2:20]2)[OH:33])[n:3][cH:4][cH:5][cH:6]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-8d5a984081234383a53a32945c01e8a2
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
Loading…