6-(3-(1H-imidazol-1-yl)propyl)-9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione → 3-(4-(2-Chloro-6-methoxyphenyl)-9-hydroxy-1,3-dioxo-2,3-dihydropyrrolo[3,4-c]carbazol-6 (1h)-yl)-n-[2-(dimethylamino)ethyl]propanamide

HRID 675917Notes

Reaction equation

HRID 675917 reaction equation
[Cl:1][c:2]1[c:3](-[c:10]2[cH:11][c:12]3[n:13]([CH2:30][CH2:31][C:32](=[O:33])[NH:34][CH2:35][CH2:36][N:37]([CH3:38])[CH3:39])[c:14]4[cH:15][cH:16][c:17]([O:28][CH3:29])[cH:18][c:19]4[c:20]3[c:21]3[c:22]2[C:23](=[O:27])[NH:24][C:25]3=[O:26])[c:4]([O:8][CH3:9])[cH:5][cH:6][cH:7]1.[OH:40][c:41]1[cH:42][cH:43][c:44]2[n:45]([CH2:46][CH2:47][CH2:48][n:49]3[cH:50][cH:51][n:52][cH:53]3)[c:54]3[cH:55][c:56](-[c:57]4[cH:58][cH:59][cH:60][cH:61][cH:62]4)[c:63]4[c:69]([c:70]3[c:71]2[cH:72]1)[C:67](=[O:68])[NH:66][C:64]4=[O:65]>>[Cl:1][c:2]1[c:3](-[c:10]2[cH:11][c:12]3[n:13]([CH2:30][CH2:31][C:32](=[O:33])[NH:34][CH2:35][CH2:36][N:37]([CH3:38])[CH3:39])[c:14]4[cH:15][cH:16][c:17]([OH:28])[cH:18][c:19]4[c:20]3[c:21]3[c:22]2[C:23](=[O:27])[NH:24][C:25]3=[O:26])[c:4]([O:8][CH3:9])[cH:5][cH:6][cH:7]1

Participants

3

Reactant 2

HCID 219806586-(3-(1H-imidazol-1-yl)propyl)-9-hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dioneHCID 91312222HCID 91312222, compound

Product 1

HCID 117569303-(4-(2-Chloro-6-methoxyphenyl)-9-hydroxy-1,3-dioxo-2,3-dihydropyrrolo[3,4-c]carbazol-6 (1h)-yl)-n-[2-(dimethylamino)ethyl]propanamide

Sources & evidence

ORD record
ord-64ee1002498948069842117eb057717b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

Loading…