Acetonitrile → N-trifluoroacetyl-8-bromo-1-isopropyl-7-methoxy-2,3,4,5-tetrahydro-1H-3-benzazepine
Reaction equation
[Br:23][N:24]1[C:25](=[O:26])[CH2:27][CH2:28][C:29]1=[O:30].[CH3:31][C:32]#[N:33].[F:1][C:2]([C:3](=[O:4])[N:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:15][cH:16][c:17]([O:19][CH3:20])[cH:18]2)[CH:10]([CH:12]([CH3:13])[CH3:14])[CH2:11]1)([F:21])[F:22]>>[F:1][C:2]([C:3](=[O:4])[N:5]1[CH2:6][CH2:7][c:8]2[c:9]([cH:15][c:16]([Br:23])[c:17]([O:19][CH3:20])[cH:18]2)[CH:10]([CH:12]([CH3:13])[CH3:14])[CH2:11]1)([F:21])[F:22]Participants
4
Sources & evidence
- ORD record
- ord-1575d41c5d954ad38e356e01aef377a3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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