3-(Pyrrolidino)phenylboronic acid → (1-Methyl-cycloheptyl)-[2-(3-pyrrolidin-1-yl-phenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-methanone

HRID 676172Notes

Reaction equation

HRID 676172 reaction equation
[Br:1][c:2]1[n:3][c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[C:11](=[O:12])[C:13]1([CH3:20])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1.[N:21]1([c:26]2[cH:27][c:28]([B:32]([OH:33])[OH:34])[cH:29][cH:30][cH:31]2)[CH2:22][CH2:23][CH2:24][CH2:25]1>>[c:2]1(-[c:28]2[cH:27][c:26]([N:21]3[CH2:22][CH2:23][CH2:24][CH2:25]3)[cH:31][cH:30][cH:29]2)[n:3][c:4]2[c:5]([n:6][cH:7]1)[nH:8][cH:9][c:10]2[C:11](=[O:12])[C:13]1([CH3:20])[CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19]1

Participants

3

Reactant 2

HCID 41926693-(Pyrrolidino)phenylboronic acidHCID 44199844(2-bromo-5H-pyrrolo[2,3-b]pyrazin-7-yl)-(1-methyl-cycloheptyl)-methanone

Product 1

HCID 59540711(1-Methyl-cycloheptyl)-[2-(3-pyrrolidin-1-yl-phenyl)-5H-pyrrolo[2,3-b]pyrazin-7-yl]-methanone

Sources & evidence

ORD record
ord-3219a5331ba949b294be6079805d0d1a
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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