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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 676192Generated: October 25, 2026

N-methyl-2-pyrrolidone → 6-((trans-4-aminocyclohexyl)amino)-N-(3-fluoro-4-pyridinyl)-8-((1-methyl-1H-pyrazol-3-yl)amino)imidazo[1,2-b]pyridazine-3-carboxamide

https://huagongshe.com/reaction/676192

Reaction equation

Participants

RoleNameHCIDCharge
ReactantN-methyl-2-pyrrolidoneHCID 13387—
Reactant1,4-DiaminocyclohexaneHCID 18374—
Reactant6-chloro-N-(3-fluoropyridin-4-yl)-8-(1-methyl-1H-pyrazol-3-ylamino)imidazo[1,2-b]pyridazine-3-carboxamideHCID 59624720—
Product6-((trans-4-aminocyclohexyl)amino)-N-(3-fluoro-4-pyridinyl)-8-((1-methyl-1H-pyrazol-3-yl)amino)imidazo[1,2-b]pyridazine-3-carboxamideHCID 59624465—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-b65ba1f4e3a3482f88a1f2184ddcb4e9
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)