HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 676394Generated: October 31, 2026
Chloride → 5-[3,5-Dichloro-4-(1-cyclohexyl-2-oxo-pyrrolidin-3-ylmethyl)-phenyl]-thiophene-2-carboxylic acid methyl ester
https://huagongshe.com/reaction/676394
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Chloride | HCID 312 | — |
| Reactant | Dichloromethane | HCID 6344 | — |
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Zinc(2+) | HCID 32051 | — |
| Reactant | Methyl 5-bromothiophene-2-carboxylate | HCID 605713 | — |
| Reactant | 3,5-Dichloro-4-((1-cyclohexyl-2-oxopyrrolidin-3-yl)methyl)phenyl trifluoromethanesulfonate | HCID 59299421 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Product | 5-[3,5-Dichloro-4-(1-cyclohexyl-2-oxo-pyrrolidin-3-ylmethyl)-phenyl]-thiophene-2-carboxylic acid methyl ester | HCID 59299387 | — |
Provenance & Evidence
| DOI | 10.1039/C8SC04228D |
|---|
| Source dataset | Training data from https://doi.org/10.1039/C8SC04228D (3/10) |
|---|
| ORD ID | ord-c0b268045cab4d7092d3d3ce2c4a33e6 |
|---|
| Source note | Training data from https://doi.org/10.1039/C8SC04228D (3/10) |
|---|
