Sodium ion → 3-chloro-6-(2-methoxyphenyl)-2-(4-trifluoromethylphenyl)-2H-indazole

HRID 676520Notes

Reaction equation

HRID 676520 reaction equation
[Br:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([Cl:21])[n:7](-[c:11]3[cH:12][cH:13][c:14]([C:17]([F:18])([F:19])[F:20])[cH:15][cH:16]3)[n:8][c:9]2[cH:10]1.[C:33](=[O:34])([O-:35])[O-:36].[CH3:22][O:23][c:24]1[c:25]([B:30]([OH:31])[OH:32])[cH:26][cH:27][cH:28][cH:29]1.[Na+:37].[Na+:38].[O:42]1[CH2:43][CH2:44][O:45][CH2:46][CH2:47]1.[Pd:39]([Cl:40])[Cl:41]>>[c:2]1(-[c:25]2[c:24]([O:23][CH3:22])[cH:29][cH:28][cH:27][cH:26]2)[cH:3][cH:4][c:5]2[c:6]([Cl:21])[n:7](-[c:11]3[cH:12][cH:13][c:14]([C:17]([F:18])([F:19])[F:20])[cH:15][cH:16]3)[n:8][c:9]2[cH:10]1

Participants

7

Reactant 6

HCID 923Sodium ion2×HCID 19660Carbonate IonHCID 24290Palladium ChlorideHCID 312751,4-DioxaneHCID 27339582-Methoxyphenylboronic acidHCID 692016176-Bromo-3-chloro-2-(4-trifluoromethylphenyl)-2H-indazole

Product 1

HCID 692033833-chloro-6-(2-methoxyphenyl)-2-(4-trifluoromethylphenyl)-2H-indazole

Sources & evidence

ORD record
ord-7c0eb0d5b1684193af3595446383e60b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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