Methyl acetoacetate → HCID 13187236, compound

HRID 67660Notes

Reaction equation

HRID 67660 reaction equation
[CH2:1]([NH:13][CH2:14][CH2:15][NH:16][CH2:17][CH2:18][NH2:19])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12].[C:20](OC)(=[O:25])[CH2:21][C:22]([CH3:24])=O>>[CH2:1]([NH:13][CH2:14][CH2:15][N:16]1[C:20](=[O:25])[CH2:21][C:22]([CH3:24])=[N:19][CH2:18][CH2:17]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH3:12]

Participants

3

Reactant 2

HCID 7757Methyl acetoacetateHCID 772911,2-Ethanediamine, N-(2-aminoethyl)-N'-dodecyl-

Product 1

HCID 13187236HCID 13187236, compound

Procedure

Into an apparatus similar to that in Example 1, were charged 271.1 g (1 mole) of N-dodecyldiethylenetriamine and 116.1 g (1 mole) of methyl acetoacetate. After 18 g of water and 32 g of methanol had been distilled off at 140° to 150° C., there was obtained 4-dodecylaminoethyl-7-methyl-3,6-dihydro-2H-1,4-diazepin-5-one in slight red liquid.

Workup

  1. distillationAfter 18 g of water and 32 g of methanol had been distilled off at 140° to 150° C.

Sources & evidence

ORD record
ord-e7738f76dfb44dc1960f67d429bbd7c4
Source dataset
uspto-grants-1982_08
Patent number
US04346087

Reaction notes

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