Chloroform → HCID 44468507, compound

HRID 676659Notes

Reaction equation

HRID 676659 reaction equation
[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([P:7]2(=[S:8])[S:9][P:11](=[S:12])([c:13]3[cH:14][cH:15][c:16]([O:17][CH3:18])[cH:19][cH:20]3)[S:10]2)[cH:21][cH:22]1.[CH3:57][O:58][CH2:59][CH2:60][O:61][CH3:62].[CH:63]([Cl:64])([Cl:65])[Cl:66].[F:23][CH:24]([c:25]1[n:26][n:27]([CH2:33][C:34](=[O:35])[N:36]2[CH2:37][CH2:38][CH:39]([c:42]3[s:43][cH:44][c:45]([C:47](=[O:48])[O:49][CH:50]4[CH2:51][CH2:52][CH2:53][CH2:54][CH2:55]4)[n:46]3)[CH2:40][CH2:41]2)[c:28]([CH:30]([F:31])[F:32])[cH:29]1)[F:56]>>[S:10]=[C:34]([CH2:33][n:27]1[n:26][c:25]([CH:24]([F:23])[F:56])[cH:29][c:28]1[CH:30]([F:31])[F:32])[N:36]1[CH2:37][CH2:38][CH:39]([c:42]2[s:43][cH:44][c:45]([C:47](=[O:48])[O:49][CH:50]3[CH2:51][CH2:52][CH2:53][CH2:54][CH2:55]3)[n:46]2)[CH2:40][CH2:41]1

Participants

5

Reactant 4

HCID 6212ChloroformHCID 80711,2-DimethoxyethaneHCID 87949Lawesson's reagentHCID 66911494Cyclohexyl 2-(1-{[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl}piperidin-4-yl)-1,3-thiazole-4-carboxylate

Product 1

HCID 44468507HCID 44468507, compound

Sources & evidence

ORD record
ord-1c4c2a48a44b4a9aa3d6028664f33719
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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