Methyl acetoacetate → HCID 13146516, compound

HRID 67674Notes

Reaction equation

HRID 67674 reaction equation
[CH2:1]([NH:15][CH2:16][CH2:17][NH:18][CH2:19][CH2:20][NH2:21])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].[C:22](OC)(=[O:27])[CH2:23][C:24]([CH3:26])=O>>[CH2:1]([NH:15][CH2:16][CH2:17][N:18]1[C:22](=[O:27])[CH2:23][C:24]([CH3:26])=[N:21][CH2:20][CH2:19]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14]

Participants

3

Reactant 2

HCID 7757Methyl acetoacetateHCID 12803361N-tetradecyldiethylenetriamine

Product 1

HCID 13146516HCID 13146516, compound

Procedure

Into an apparatus similar to that in Example 1, were charged 299.5 g (1 mole) of N-tetradecyldiethylenetriamine and 116.1 g (1 mole) of methyl acetoacetate. At 150° to 160° C., 18 g of water and 32 g of methanol were distilled off to obtain 4-tetradecylaminoethyl-7-methyl-3,6-dihydro-2H-1,4-diazepin-5-one.

Workup

  1. distillationAt 150° to 160° C., 18 g of water and 32 g of methanol were distilled off

Sources & evidence

ORD record
ord-d64e5594602b4fe687767b9ba4e896f2
Source dataset
uspto-grants-1982_08
Patent number
US04346087

Reaction notes

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