HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl 2-Formylpropionate → 4-(2-hydroxyhexadecyl)aminoethyl-6-methyl-3,6-dihydro-2H-1,4-diazepin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl 2-Formylpropionate | HCID 10898741 | — |
| Reactant | 1-({2-[(2-Aminoethyl)amino]ethyl}amino)hexadecan-2-OL | HCID 20148361 | — |
| Product | 4-(2-hydroxyhexadecyl)aminoethyl-6-methyl-3,6-dihydro-2H-1,4-diazepin-5-one | HCID 54556236 | — |
Reaction Steps
Into an apparatus similar to that in Example 1, were charged 339.5 g (1 mole) of N-(2-hydroxy)hexadecyldiethylenetriamine and 130.1 g of ethyl 2-formylpropionate. At 140° to 150° C., 18 g of water and 46 g of ethanol were distilled off to obtain 4-(2-hydroxyhexadecyl)aminoethyl-6-methyl-3,6-dihydro-2H-1,4-diazepin-5-one.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04346087 |
| Source dataset | uspto-grants-1982_08 |
| ORD ID | ord-71e10a754d92408f843c430ca6130f76 |
| Source note | uspto-grants-1982_08 |