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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 676839Generated: October 29, 2026

Dichloromethane → 4-(1,4-dimethylpyrazol-5-yl)-N-[1-(1,3-dioxoisoindol-2-yl)-3-[2-(trifluoromethyl)phenyl]propan-2-yl]-5-ethylthiophene-2-carboxamide

https://huagongshe.com/reaction/676839

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantHexafluorophosphateHCID 9886—
ReactantDiisopropylethylamineHCID 81531—
ReactantBromotripyrrolidin-1-ylphosphoniumHCID 2733180—
Reactant4-(1,4-dimethyl-1H-pyrazol-5-yl)-5-ethyl-2-thiophenecarboxylic acidHCID 57826638—
Reactant2-[2-amino-3-[2-(trifluoromethyl)phenyl]propyl]isoindole-1,3-dioneHCID 178510762—
Product4-(1,4-dimethylpyrazol-5-yl)-N-[1-(1,3-dioxoisoindol-2-yl)-3-[2-(trifluoromethyl)phenyl]propan-2-yl]-5-ethylthiophene-2-carboxamideHCID 76576552—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-493cec12f86641e2931c3180aa9f5264
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)