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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 677104Generated: October 30, 2026

Toluene → 4-[3-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-4-phenylpyrrolidine-1-carbonyl]-1,3-oxazolidin-2-one

https://huagongshe.com/reaction/677104

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTolueneHCID 1140—
ReactantDichloromethaneHCID 6344—
ReactantPhosgeneHCID 6371—
ReactantTriethylamineHCID 8471—
Reactant2-Amino-1-[3-[1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-phenylpyrrolidin-1-yl]-3-hydroxypropan-1-oneHCID 11352312—
Product4-[3-[1-[3,5-Bis(trifluoromethyl)phenyl]ethoxy]-4-phenylpyrrolidine-1-carbonyl]-1,3-oxazolidin-2-oneHCID 16662225—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-5c1cb8f9261940858f896eb74d5c7b49
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)