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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 677191Generated: October 29, 2026

Ammonium → 1-(1,1-Dimethylethyl) 4-methyl 4-[(4-chlorophenyl)methyl]-1,4-piperidinedicarboxylate

https://huagongshe.com/reaction/677191

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAmmoniumHCID 223—
ReactantChlorideHCID 312—
ReactantIsopropylamineHCID 6363—
Reactant1-Chloro-4-(chloromethyl)benzeneHCID 7723—
ReactantTetrahydrofuranHCID 8028—
ReactantHexamethylphosphoramideHCID 12679—
ReactantLithium ionHCID 28486—
Reactant1-N-Boc-4-Piperidinecarboxylic acid methyl esterHCID 392870—
ReactantDiisopropylamideHCID 5062348—
ReactantButyllithiumHCID 178418339—
Product1-(1,1-Dimethylethyl) 4-methyl 4-[(4-chlorophenyl)methyl]-1,4-piperidinedicarboxylateHCID 59840467—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (3/10)
ORD IDord-0446c530db594bb9b132f69a0a3c6443
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (3/10)