Dichloromethane → Tert-butyl 4,4-difluoro-2-formylpyrrolidine-1-carboxylate

HRID 677231Notes

Reaction equation

HRID 677231 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH2:15][OH:16])[CH2:10][C:11]([F:13])([F:14])[CH2:12]1.[Cl:17][CH2:18][Cl:19]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH:9]([CH:15]=[O:16])[CH2:10][C:11]([F:13])([F:14])[CH2:12]1

Participants

3

Reactant 2

HCID 6344DichloromethaneHCID 22001352Tert-butyl 4,4-difluoro-2-(hydroxymethyl)pyrrolidine-1-carboxylate

Product 1

HCID 23511694Tert-butyl 4,4-difluoro-2-formylpyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-bc52fcd4ae5e4461a2913066ac8a38f0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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