HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glyoxylic Acid → 4-Amino-3-sulfanyl-4,5-dihydro-1,2,4-triazin-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glyoxylic Acid | HCID 760 | — |
| Reactant | Thiocarbohydrazide | HCID 2724189 | — |
| Solvent | Water | HCID 962 | — |
| Product | 4-Amino-3-sulfanyl-4,5-dihydro-1,2,4-triazin-5-one | HCID 13061842 | — |
Reaction Steps
A solution of 22 parts glyoxylic acid in 22 parts water is slowly added to a hot, stirred solution of 32 parts thiocarbohydrazide in 350 parts water. The resulting mixture is refluxed until no further precipitate is formed. Upon cooling, essentially pure 4-amino-2,3-dihydro-3-thiono-as-triazin-5(4H)-one having a melting point of 211°-215° C. is obtained by filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04346220 |
| Source dataset | uspto-grants-1982_08 |
| ORD ID | ord-7c3be85c692f4eab9ae18d1027611f2f |
| Source note | uspto-grants-1982_08 |