4-Fluorobenzylamine → N-(4-fluorobenzyl)-2-(2-dimethylsulfamoylphenyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide

HRID 677254Notes

Reaction equation

HRID 677254 reaction equation
[CH2:1]([O:2][C:4](=[O:5])[c:6]1[n:7][c:8](-[c:15]2[c:16]([S:21]([N:22]([CH3:23])[CH3:24])(=[O:25])=[O:26])[cH:17][cH:18][cH:19][cH:20]2)[n:9]([CH3:14])[c:10](=[O:13])[c:11]1[OH:12])[CH3:3].[F:27][c:28]1[cH:29][cH:30][c:31]([CH2:32][NH2:33])[cH:34][cH:35]1>>[C:4](=[O:5])([c:6]1[n:7][c:8](-[c:15]2[c:16]([S:21]([N:22]([CH3:23])[CH3:24])(=[O:25])=[O:26])[cH:17][cH:18][cH:19][cH:20]2)[n:9]([CH3:14])[c:10](=[O:13])[c:11]1[OH:12])[NH:33][CH2:32][c:31]1[cH:30][cH:29][c:28]([F:27])[cH:35][cH:34]1

Participants

3

Reactant 2

HCID 673264-FluorobenzylamineHCID 546914412-(2-Dimethylsulfamoyl-phenyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydro-pyrimidine-4-carboxylic acid ethyl ester

Product 1

HCID 54711182N-(4-fluorobenzyl)-2-(2-dimethylsulfamoylphenyl)-5-hydroxy-1-methyl-6-oxo-1,6-dihydropyrimidine-4-carboxamide

Sources & evidence

ORD record
ord-e07e7a52dd3d49b6a19b65699459f068
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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