4-(4-tert-butoxycarbonyl-1-piperazinyl)methyl-2-(4-fluorobenzyl)-6-(3-fluoro-4-methoxyphenyl)-2H-pyridazin-3-one → 4-aminomethyl-2-(4-fluorobenzyl)-6-(3-fluoro-4-methoxyphenyl)-2H-pyridazin-3-one
Reaction equation
[C:1]([O:2][C:3]([N:4]1[CH2:5][CH2:6][N:11]([CH2:14][c:15]2[c:16](=[O:38])[n:17]([CH2:30][c:31]3[cH:32][cH:33][c:34]([F:37])[cH:35][cH:36]3)[n:18][c:19](-[c:21]3[cH:22][c:23]([F:29])[c:24]([O:27][CH3:28])[cH:25][cH:26]3)[cH:20]2)[CH2:7][CH2:8]1)=[O:9])([CH3:10])([CH3:12])[CH3:13].[F:39][c:40]1[cH:41][cH:42][c:43]([CH2:44][n:45]2[c:46](=[O:47])[c:48]([CH2:49][O:50][S:51]([CH3:52])(=[O:53])=[O:54])[cH:55][c:56](-[c:57]3[cH:58][cH:59][c:60]([O:61][CH3:62])[c:63]([F:64])[cH:65]3)[n:66]2)[cH:67][cH:68]1>>[NH2:11][CH2:14][c:15]1[c:16](=[O:38])[n:17]([CH2:30][c:31]2[cH:32][cH:33][c:34]([F:37])[cH:35][cH:36]2)[n:18][c:19](-[c:21]2[cH:22][c:23]([F:29])[c:24]([O:27][CH3:28])[cH:25][cH:26]2)[cH:20]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-c3d6d91b69f44f5091972ba42ce0d3ed
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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