Water → 6-(1H-Indol-4-yl)-1-[(4-methylphenyl)sulfonyl]-1H-indazole-4-carbonitrile

HRID 677305Notes

Reaction equation

HRID 677305 reaction equation
[Br:1][c:2]1[cH:3][c:4]([C:21]#[N:22])[c:5]2[cH:6][n:7][n:8]([S:11](=[O:12])(=[O:13])[c:14]3[cH:15][cH:16][c:17]([CH3:20])[cH:18][cH:19]3)[c:9]2[cH:10]1.[CH2:42]1[O:43][CH2:44][CH2:45][O:46][CH2:47]1.[CH3:23][C:24]1([CH3:25])[C:26]([CH3:27])([CH3:28])[O:29][B:30]([c:31]2[c:32]3[cH:33][cH:34][nH:35][c:36]3[cH:37][cH:38][cH:39]2)[O:40]1.[OH2:41]>>[c:2]1(-[c:31]2[c:32]3[cH:33][cH:34][nH:35][c:36]3[cH:37][cH:38][cH:39]2)[cH:3][c:4]([C:21]#[N:22])[c:5]2[cH:6][n:7][n:8]([S:11](=[O:12])(=[O:13])[c:14]3[cH:15][cH:16][c:17]([CH3:20])[cH:18][cH:19]3)[c:9]2[cH:10]1

Participants

5

Reactant 4

HCID 962WaterHCID 312751,4-DioxaneHCID 113224711H-Indole-4-boronic acid, pinacol esterHCID 666914596-bromo-1-(4-methylbenzenesulfonyl)-1H-indazole-4-carbonitrile

Product 1

HCID 667767806-(1H-Indol-4-yl)-1-[(4-methylphenyl)sulfonyl]-1H-indazole-4-carbonitrile

Sources & evidence

ORD record
ord-307866c890434b3bac1e7135c2adde7d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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