4-(4-Chloro-3-dimethylsulfamoylphenyl)-3-methyl-2-phenyliminothiazolidin-4-ol hydrobromide → HCID 20527373, compound

HRID 67745Notes

Reaction equation

HRID 67745 reaction equation
[BrH:1].[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2(O)[CH2:13][S:12][C:11](=[N:14][C:15]3[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=3)[N:10]2[CH3:21])=[CH:5][C:4]=1[S:23](=[O:28])(=[O:27])[N:24]([CH3:26])[CH3:25]>C(O)(=O)C>[BrH:1].[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:10]([CH3:21])[C:11](=[N:14][C:15]3[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=3)[S:12][CH:13]=2)=[CH:5][C:4]=1[S:23](=[O:28])(=[O:27])[N:24]([CH3:25])[CH3:26]

Participants

3

Reactant 1

HCID 205274234-(4-Chloro-3-dimethylsulfamoylphenyl)-3-methyl-2-phenyliminothiazolidin-4-ol hydrobromide

Product 1

HCID 20527373HCID 20527373, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

10.1 g (0.02 mole) of 4-(4-chloro-3-dimethylsulfamoylphenyl)-3-methyl-2-phenyliminothiazolidin-4-ol hydrobromide in 80 ml of glacial acetic acid are heated to the boil over a period of 20 minutes. After cooling, crystallization is brought to completion by adding about 150 ml of diisopropyl ether, the mixture is stirred for a further one hour at room temperature and the product is filtered off. Colorless crystals; melting point 258°-260° C. (with decomposition).

Workup

  1. temperatureAfter cooling
  2. customcrystallization
  3. additionby adding about 150 ml of diisopropyl ether
  4. filtrationthe product is filtered off

Sources & evidence

ORD record
ord-73c90aedbaf74bb08c7422460788cefe
Source dataset
uspto-grants-1982_08
Patent number
US04346088

Reaction notes

Loading…