HCID 70537519, compound → 2-(4-Diethylaminophenyl-imino)-4-(4-chloro-3-dimethylsulfamoylphenyl)-3-methyl-4-thiazoline hydrobromide

HRID 67751Notes

Reaction equation

HRID 67751 reaction equation
[BrH:1].[CH2:2]([N:4]([CH2:32][CH3:33])[C:5]1[CH:10]=[CH:9][C:8]([N:11]=[C:12]2[N:16]([CH3:17])[C:15]([C:19]3[CH:24]=[CH:23][C:22]([Cl:25])=[C:21]([S:26](=[O:31])(=[O:30])[N:27]([CH3:29])[CH3:28])[CH:20]=3)(O)[CH2:14][S:13]2)=[CH:7][CH:6]=1)[CH3:3]>C(O)(=O)C>[BrH:1].[CH2:32]([N:4]([CH2:2][CH3:3])[C:5]1[CH:6]=[CH:7][C:8]([N:11]=[C:12]2[N:16]([CH3:17])[C:15]([C:19]3[CH:24]=[CH:23][C:22]([Cl:25])=[C:21]([S:26](=[O:30])(=[O:31])[N:27]([CH3:28])[CH3:29])[CH:20]=3)=[CH:14][S:13]2)=[CH:9][CH:10]=1)[CH3:33]

Participants

3

Reactant 1

HCID 70537519HCID 70537519, compound

Product 1

HCID 205271652-(4-Diethylaminophenyl-imino)-4-(4-chloro-3-dimethylsulfamoylphenyl)-3-methyl-4-thiazoline hydrobromide

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Obtained by a procedure analogous to that indicated in Example 1 (b), from 2-(4-diethylaminophenyl-imino)-4-(4-chloro-3-dimethylsulfamoylphenyl)-3-methyl-thiazolidin-4-ol hydrobromide. After heating in glacial acetic acid, the solvent is distilled off until the volume is 30 ml, and the desired product is precipitated with 150 ml of diisopropyl ether. Colorless crystals; melting point 257° C. (with decomposition).

Workup

  1. customObtained by a procedure analogous to
  2. distillationthe solvent is distilled off until the volume
  3. customthe desired product is precipitated with 150 ml of diisopropyl ether

Sources & evidence

ORD record
ord-0ac86af625ab4d8cad13f222aa18b284
Source dataset
uspto-grants-1982_08
Patent number
US04346088

Reaction notes

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