3-(2-Methoxyphenyl)-5-methyl-1,2-oxazole-4-carboxylic acid → Methyl 2-amino-5-chloro-4-(4-(3-(2-methoxyphenyl)-5-methylisoxazole-4-carbonyl)piperazin-1-yl)benzoate

HRID 677524Notes

Reaction equation

HRID 677524 reaction equation
[CH3:1][O:2][c:3]1[c:4](-[c:9]2[n:10][o:11][c:12]([CH3:17])[c:13]2[C:14](=[O:15])[OH:16])[cH:5][cH:6][cH:7][cH:8]1.[NH2:18][c:19]1[c:20]([C:21](=[O:22])[O:23][CH3:24])[cH:25][c:26]([Cl:35])[c:27]([N:29]2[CH2:30][CH2:31][NH:32][CH2:33][CH2:34]2)[cH:28]1>>[CH3:1][O:2][c:3]1[c:4](-[c:9]2[n:10][o:11][c:12]([CH3:17])[c:13]2[C:14](=[O:16])[N:32]2[CH2:31][CH2:30][N:29]([c:27]3[c:26]([Cl:35])[cH:25][c:20]([C:21](=[O:22])[O:23][CH3:24])[c:19]([NH2:18])[cH:28]3)[CH2:34][CH2:33]2)[cH:5][cH:6][cH:7][cH:8]1

Participants

3

Reactant 2

HCID 64841003-(2-Methoxyphenyl)-5-methyl-1,2-oxazole-4-carboxylic acidHCID 66691661Methyl 2-amino-5-chloro-4-(piperazin-1-yl)benzoate

Product 1

HCID 66691522Methyl 2-amino-5-chloro-4-(4-(3-(2-methoxyphenyl)-5-methylisoxazole-4-carbonyl)piperazin-1-yl)benzoate

Sources & evidence

ORD record
ord-a0ed1895789c4751859845c101955a32
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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