Acetic Acid → HCID 20527222, compound

HRID 67769Notes

Reaction equation

HRID 67769 reaction equation
[BrH:1].[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2(O)[CH2:13][S:12][CH:11](C3C=CC=CC=3C)[N:10]2[CH3:21])=[CH:5][C:4]=1[S:23](=[O:32])(=[O:31])[N:24]([CH2:28][CH2:29][CH3:30])[CH2:25][CH2:26][CH3:27].[C:33](O)(=O)[CH3:34]>>[BrH:1].[Cl:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[N:10]([CH3:21])[C:11](=[N:10][C:9]3[CH:6]=[CH:5][CH:4]=[CH:3][C:33]=3[CH3:34])[S:12][CH:13]=2)=[CH:5][C:4]=1[S:23](=[O:31])(=[O:32])[N:24]([CH2:25][CH2:26][CH3:27])[CH2:28][CH2:29][CH3:30]

Participants

3

Reactant 2

HCID 176Acetic AcidHCID 20527459HCID 20527459, compound

Product 1

HCID 20527222HCID 20527222, compound

Procedure

Obtained by a procedure analogous to that indicated in Example 1(b), from 4-(4-chloro-3-dipropylsulfamoylphenyl)-3-methyl-2-(2-methylphenyl)-thiazolidin-4-ol hydrobromide, by boiling in glacial acetic acid for 2 hours. The reaction mixture is concentrated, water is added to the residue and the crystals are filtered off. Melting point 218°-220° C.

Workup

  1. customObtained by a procedure analogous to
  2. concentrationThe reaction mixture is concentrated
  3. additionwater is added to the residue
  4. filtrationthe crystals are filtered off

Sources & evidence

ORD record
ord-f65ca459063c4ce7b045337655c9a4ad
Source dataset
uspto-grants-1982_08
Patent number
US04346088

Reaction notes

Loading…