2,4-Dichloro-5-fluoropyrimidine → 2-chloro-5-fluoro-N4-(1,2,3,4-tetrahydro-1-oxonaphthalen-7-yl)-4-pyrimidineamine
Reaction equation
[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([Cl:8])[n:7]1.[NH2:10][c:11]1[cH:12][cH:13][c:14]2[c:19]([cH:20]1)[C:18](=[O:21])[CH2:17][CH2:16][CH2:15]2>>[Cl:1][c:2]1[n:3][cH:4][c:5]([F:9])[c:6]([NH:10][c:11]2[cH:12][cH:13][c:14]3[c:19]([cH:20]2)[C:18](=[O:21])[CH2:17][CH2:16][CH2:15]3)[n:7]1Participants
3
Sources & evidence
- ORD record
- ord-7e84fe577c2644869d2e858a76619cf1
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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