8-[(3-Methyl-2-thienyl)methyl]-2,8-diazaspiro[4.5]decane → 2-[2-[[1-(dimethylsulfamoyl)imidazol-2-yl]methyl]-3-[4-[[8-[(3-methylthiophen-2-yl)methyl]-2,8-diazaspiro[4.5]decan-2-yl]methyl]piperidin-1-yl]-3-oxopropyl]-N,N-dimethylimidazole-1-sulfonamide
Reaction equation
[CH3:36][c:37]1[c:38]([CH2:42][N:43]2[CH2:44][CH2:45][C:46]3([CH2:47][CH2:48][NH:49][CH2:50]3)[CH2:51][CH2:52]2)[s:39][cH:40][cH:41]1.[CH:1](=[O:2])[CH:3]1[CH2:4][CH2:5][N:6]([C:9](=[O:10])[CH:11]([CH2:12][c:13]2[n:14]([S:18](=[O:19])(=[O:20])[N:21]([CH3:22])[CH3:23])[cH:15][cH:16][n:17]2)[CH2:24][c:25]2[n:26]([S:30](=[O:31])(=[O:32])[N:33]([CH3:34])[CH3:35])[cH:27][cH:28][n:29]2)[CH2:7][CH2:8]1>>[CH2:1]([CH:3]1[CH2:4][CH2:5][N:6]([C:9](=[O:10])[CH:11]([CH2:12][c:13]2[n:14]([S:18](=[O:19])(=[O:20])[N:21]([CH3:22])[CH3:23])[cH:15][cH:16][n:17]2)[CH2:24][c:25]2[n:26]([S:30](=[O:31])(=[O:32])[N:33]([CH3:34])[CH3:35])[cH:27][cH:28][n:29]2)[CH2:7][CH2:8]1)[N:49]1[CH2:48][CH2:47][C:46]2([CH2:45][CH2:44][N:43]([CH2:42][c:38]3[c:37]([CH3:36])[cH:41][cH:40][s:39]3)[CH2:52][CH2:51]2)[CH2:50]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-d10d3a3cf3034723b84379a9d9192e9d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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