2-Aminopyrimidine-5-boronic acid, pinacol ester → 5-{1-[4-Methyl-6-(4-trifluoromethyl-phenyl)-pyrimidin-2-yl]-1H-imidazol-4-yl}-pyrimidin-2-ylamine
Reaction equation
[Br:1][c:2]1[n:3][cH:4][n:5](-[c:7]2[n:8][c:9](-[c:14]3[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]3)[cH:10][c:11]([CH3:13])[n:12]2)[cH:6]1.[NH2:24][c:25]1[n:26][cH:27][c:28]([B:31]2[O:32][C:33]([CH3:34])([CH3:35])[C:36]([CH3:37])([CH3:38])[O:39]2)[cH:29][n:30]1>>[c:2]1(-[c:28]2[cH:27][n:26][c:25]([NH2:24])[n:30][cH:29]2)[n:3][cH:4][n:5](-[c:7]2[n:8][c:9](-[c:14]3[cH:15][cH:16][c:17]([C:20]([F:21])([F:22])[F:23])[cH:18][cH:19]3)[cH:10][c:11]([CH3:13])[n:12]2)[cH:6]1Participants
3
Sources & evidence
- ORD record
- ord-c9f30fb6061f4ebe9a820cdd09ad9012
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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