(3-Chloro-phenyl)-5-cyclopropylmethoxy-3-trifluoromethyl-pyrazine-2-carboxylic acid (2-cyclopropyl-2-hydroxy-propyl)-amide → 6-(3,4-Dichloro-phenyl)-5-cyclopropylmethoxy-3-trifluoromethyl-pyrazine-2-carboxylic acid (2-cyclopropyl-2-hydroxy-propyl)-amide
Reaction equation
[CH3:33][O:34][C:35]([c:36]1[c:37]([C:38]([F:39])([F:40])[F:41])[n:42][c:43]([Br:44])[c:45](-[c:46]2[cH:47][cH:48][c:49]([Cl:54])[c:50]([Cl:51])[cH:52]2)[n:53]1)=[O:55].[CH:1]1([C:4]([CH2:5][NH:6][C:7](=[O:8])[c:9]2[n:10][c:11](-[c:24]3[cH:25][c:26]([Cl:30])[cH:27][cH:28][cH:29]3)[c:12]([O:19][CH2:20][CH:21]3[CH2:22][CH2:23]3)[n:13][c:14]2[C:15]([F:16])([F:17])[F:18])([CH3:31])[OH:32])[CH2:2][CH2:3]1>>[CH:1]1([C:4]([CH2:5][NH:6][C:7](=[O:8])[c:9]2[n:10][c:11](-[c:24]3[cH:25][c:26]([Cl:30])[c:27]([Cl:54])[cH:28][cH:29]3)[c:12]([O:19][CH2:20][CH:21]3[CH2:22][CH2:23]3)[n:13][c:14]2[C:15]([F:16])([F:17])[F:18])([CH3:31])[OH:32])[CH2:2][CH2:3]1Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-3556513dda2c4295a02162a0f87feadb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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