Ethanol → [2-[5-(aminomethyl)-7-(cyclopentylamino)-1H-indol-2-yl]-4,5-dihydro-1,3-thiazol-4-yl]methanol

HRID 678468Notes

Reaction equation

HRID 678468 reaction equation
[CH3:38][CH2:39][OH:40].[CH:1]1([NH:6][c:7]2[cH:8][c:9]([CH2:23][N:24]3[C:25](=[O:26])[c:27]4[c:28]([cH:29][cH:30][cH:31][cH:32]4)[C:33]3=[O:34])[cH:10][c:11]3[cH:12][c:13]([C:16]4=[N:20][CH:19]([CH2:21][OH:22])[CH2:18][S:17]4)[nH:14][c:15]23)[CH2:2][CH2:3][CH2:4][CH2:5]1.[NH2:36][NH2:37].[OH2:35]>>[CH:1]1([NH:6][c:7]2[cH:8][c:9]([CH2:23][NH2:24])[cH:10][c:11]3[cH:12][c:13]([C:16]4=[N:20][CH:19]([CH2:21][OH:22])[CH2:18][S:17]4)[nH:14][c:15]23)[CH2:2][CH2:3][CH2:4][CH2:5]1

Participants

5

Reactant 4

HCID 702EthanolHCID 962WaterHCID 9321HydrazineHCID 775045872-[[7-(cyclopentylamino)-2-[4-(hydroxymethyl)-4,5-dihydro-1,3-thiazol-2-yl]-1H-indol-5-yl]methyl]isoindole-1,3-dione

Product 1

HCID 68486075[2-[5-(aminomethyl)-7-(cyclopentylamino)-1H-indol-2-yl]-4,5-dihydro-1,3-thiazol-4-yl]methanol

Sources & evidence

ORD record
ord-e893b593a2764ab5be442906027937c1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (3/10)

Reaction notes

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