反应详情

A mixture of 5.0 g. of 2-(3-amino-2-pyrazolin-1-yl)-6-chloropyridine (prepared as described in Example 3) and 25 ml. of a mixture of formic acid and acetic anhydride (Feiser and Feiser, Reagents for Organic Synthesis, Vol. 1, page 4) at room temperature gives an immediate yellow precipitate. The precipitate is collected by filtration then is recrystallized from acetone-hexane to give 3.05 g. of the product of the Example as off-white crystals, m.p. 190°-192° C.

1. additionA mixture of 5.0 g
2. customgives an immediate yellow precipitate
3. filtrationThe precipitate is collected by filtration
4. customthen is recrystallized from acetone-hexane
5. customto give 3.05 g