4-(Difluoromethoxy)benzyl Bromide → N-Benzyl-5-(4-(4-(difluoromethoxy)benzyloxy)-2-oxopyridin-1(2H)-yl)-3-methylthiophene-2-carboxamide
Reaction equation
[Br:1][CH2:2][c:3]1[cH:4][cH:5][c:6]([O:9][CH:10]([F:11])[F:12])[cH:7][cH:8]1.[CH2:13]([c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1)[NH:20][C:21](=[O:22])[c:23]1[s:24][c:25](-[n:29]2[c:30](=[O:36])[cH:31][c:32]([OH:35])[cH:33][cH:34]2)[cH:26][c:27]1[CH3:28]>>[CH2:2]([c:3]1[cH:4][cH:5][c:6]([O:9][CH:10]([F:11])[F:12])[cH:7][cH:8]1)[O:35][c:32]1[cH:31][c:30](=[O:36])[n:29](-[c:25]2[s:24][c:23]([C:21]([NH:20][CH2:13][c:14]3[cH:15][cH:16][cH:17][cH:18][cH:19]3)=[O:22])[c:27]([CH3:28])[cH:26]2)[cH:34][cH:33]1Participants
3
Sources & evidence
- ORD record
- ord-ab8d6a19b50c41569f1c6afa814a4ba7
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (3/10)
Reaction notes
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