Acetic Anhydride → HCID 20267417, compound

HRID 67920Notes

Reaction equation

HRID 67920 reaction equation
[CH2:1]([C:6]1[CH:11]=[C:10]([O:12][CH3:13])[C:9]([O:14][CH3:15])=[CH:8][C:7]=1[OH:16])[CH2:2][C:3]([CH3:5])=[CH2:4].[C:17](OC(=O)C)(=[O:19])[CH3:18]>N1C=CC=CC=1>[C:17]([O:16][C:7]1[CH:8]=[C:9]([O:14][CH3:15])[C:10]([O:12][CH3:13])=[CH:11][C:6]=1[CH2:1][CH2:2][C:3]([CH3:5])=[CH2:4])(=[O:19])[CH3:18]

Participants

4

Reactant 2

HCID 7918Acetic AnhydrideHCID 20267416HCID 20267416, compound

Product 1

HCID 20267417HCID 20267417, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

100 mg. of the phenol of Example 1 was combined with 2 ml. of pyridine and 1 ml. of acetic anhydride for one hour. The reaction mixture was extracted with ether and the ether extract washed sequentially with water, 1NHCl, water and saturated salt solution then dried over sodium sulfate. Upon evaporation 0.11 grams of the acetate was recovered.

Workup

  1. extractionThe reaction mixture was extracted with ether
  2. extractionthe ether extract
  3. washwashed sequentially with water
  4. dry with material1NHCl, water and saturated salt solution then dried over sodium sulfate
  5. customUpon evaporation 0.11 grams of the acetate
  6. customwas recovered

Sources & evidence

ORD record
ord-a5240288f55b43b0934d7eb28861398c
Source dataset
uspto-grants-1982_08
Patent number
US04347256

Reaction notes

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